SYNTHESIS AND STRUCTURAL, CONFORMATIONAL AND PHARMACOLOGICAL STUDY OF N-BETA (OR GAMMA)ACYLOXYALKYLNORTROPINONES

被引：10

作者：

IZQUIERDO, ML

GALVEZ, E

BURGOS, C

VAQUERO, JJ

FLORENCIO, F

ORJALES, A

INNERARITY, A

机构：

[1] UNIV ALCALA HENARES,DEPT QUIM ORGAN,ALCALA HENARES,SPAIN

[2] CSIC,INST ROCASOLANO,DEPT RAYOS X,E-28006 MADRID,SPAIN

[3] FAES SA,BILBAO,SPAIN

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 24卷 / 02期

关键词：

D O I：

10.1016/0223-5234(89)90105-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：123 / 129

页数：7

共 28 条

[1] CONFORMATIONAL STUDY OF N-SUBSTITUTED 8-AZABICYCLO[3.2.1]OCTAN-3-ONES [J].

ARIAS, MS ;

GALVEZ, E ;

IZQUIERDO, ML ;

BURGOS, C .

JOURNAL OF MOLECULAR STRUCTURE, 1986, 147 (3-4) :381-388

[2] STRUCTURE AND ACTIVITY OF MUSCARINIC STIMULANTS [J].

BAKER, RW ;

CHOTHIA, CH ;

PAULING, P ;

PETCHER, TJ .

NATURE, 1971, 230 (5294) :439-&

[3]

BEBBINGTON A., 1965, ADVANCE DRUG RES, V2, P143

[4] SYNTHESIS AND STRUCTURAL STUDY OF N-(8-ISOPROPYLNORTROPAN-3-ALPHA-YL)-2-METHOXY-4-AMINO-5-CHLOROBENZAMIDE [J].

CABEZAS, N ;

MARTINEZ, M ;

GALVEZ, E ;

ARIAS, MS ;

FLORENCIO, F ;

GARCIABLANCO, S .

JOURNAL OF MOLECULAR STRUCTURE, 1988, 172 :381-394

[5] 6-METHYL-6-AZABICYCLO[3.2.1]OCTAN-3-ALPHA-OL 2,2-DIPHENYLPROPIONATE (AZAPROPHEN), A HIGHLY POTENT ANTIMUSCARINIC AGENT [J].

CARROLL, FI ;

ABRAHAM, P ;

PARHAM, K ;

GRIFFITH, RC ;

AHMAD, A ;

RICHARD, MM ;

PADILLA, FN ;

WITKIN, JM ;

CHIANG, PK .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (05) :805-809

[6] CONFORMATIONAL-ANALYSIS OF TROPANE ANALOG OF PETHIDINE AND RELATED COMPOUNDS BY H-1 NMR-SPECTROSCOPY [J].

CASY, AF ;

COATES, JE .

ORGANIC MAGNETIC RESONANCE, 1974, 6 (08) :441-444

[7] 1,3-DIPOLAR CHARACTER OF 6-MEMBERED AROMATIC RINGS .18. ADDUCTS FROM 3-OXIDO-1-PHENYLPYRIDINIUM AND THEIR QUATERNIZATION AND CONVERSION INTO TROPONE DERIVATIVES [J].

DENNIS, N ;

KATRITZKY, AR ;

PARTON, SK ;

NOMURA, Y ;

TAKAHASHI, Y ;

TAKEUCHI, Y .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1976, (21) :2289-2296

[8] TRICYCLIC COMPOUNDS AS SELECTIVE ANTIMUSCARINICS .1. STRUCTURAL REQUIREMENTS FOR SELECTIVITY TOWARD THE MUSCARINIC ACETYLCHOLINE-RECEPTOR IN A SERIES OF PIRENZEPINE AND IMIPRAMINE ANALOGS [J].

EBERLEIN, WG ;

TRUMMLITZ, G ;

ENGEL, WW ;

SCHMIDT, G ;

PELZER, H ;

MAYER, N .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (08) :1378-1382

[9] CONCERNING 2-CARBOMETHOXYTROPINONE [J].

FINDLAY, SP .

JOURNAL OF ORGANIC CHEMISTRY, 1957, 22 (11) :1385-1394

[10] MOLECULAR MODIFICATION OF ANTICHOLINERGICS AS PROBES FOR MUSCARINIC RECEPTORS .3. CONFORMATIONALLY RESTRICTED ANALOGS OF BENACTYZINE [J].

FLAVIN, MT ;

LU, MC ;

THOMPSON, EB ;

BHARGAVA, HN .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (02) :278-285

← 1 2 3 →