学术探索
学术期刊
新闻热点
数据分析
智能评审

UNUSUAL STRUCTURAL FEATURES OF 2',3'-DIDEOXYCYTIDINE, AN INHIBITOR OF THE HIV (AIDS) VIRUS

被引：42
作者：
BIRNBAUM, GI [1 ]
LIN, TS [1 ]
PRUSOFF, WH [1 ]
机构：
[1] YALE UNIV,SCH MED,DEPT PHARMACOL,NEW HAVEN,CT 06510
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1988年 / 151卷 / 01期
关键词：
D O I：
10.1016/0006-291X(88)90637-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：608 / 614
页数：7
相关论文
共 28 条
[1]   SYSTEMATIC ANALYSIS OF STRUCTURAL DATA AS A RESEARCH TECHNIQUE IN ORGANIC-CHEMISTRY [J].
ALLEN, FH ;
KENNARD, O ;
TAYLOR, R .
ACCOUNTS OF CHEMICAL RESEARCH, 1983, 16 (05) :146-153
[2]   BOTH 2',3'-DIDEOXYTHYMIDINE AND ITS 2',3'-UNSATURATED DERIVATIVE (2',3'-DI-DEOXYTHYMIDINENE) ARE POTENT AND SELECTIVE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-REPLICATION INVITRO [J].
BABA, M ;
PAUWELS, R ;
HERDEWIJN, P ;
DECLERCQ, E ;
DESMYTER, J ;
VANDEPUTTE, M .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 142 (01) :128-134
[3]   THE 2',3'-DIDEOXYRIBOSIDE OF 2,6-DIAMINOPURINE SELECTIVELY INHIBITS HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) REPLICATION INVITRO [J].
BALZARINI, J ;
PAUWELS, R ;
BABA, M ;
ROBINS, MJ ;
ZOU, R ;
HERDEWIJN, P ;
DECLERCQ, E .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 145 (01) :269-276
[4]   THE 2',3'-DIDEOXYRIBOSIDE OF 2,6-DIAMINOPURINE AND ITS 2',3'-DIDEHYDRO DERIVATIVE INHIBIT THE DEAMINATION OF 2',3'-DIDEOXYADENOSINE, AN INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) REPLICATION [J].
BALZARINI, J ;
ROBINS, MJ ;
ZOU, R ;
HERDEWIJN, P ;
DECLERCQ, E .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 145 (01) :277-283
[5]   POTENT AND SELECTIVE ANTI-HTLV-III/LAV ACTIVITY OF 2',3'-DIDEOXYCYTIDINENE, THE 2',3'-UNSATURATED DERIVATIVE OF 2',3'-DIDEOXYCYTIDINE [J].
BALZARINI, J ;
PAUWELS, R ;
HERDEWIJN, P ;
DECLERCQ, E ;
COONEY, DA ;
KANG, GJ ;
DALAL, M ;
JOHNS, DG ;
BRODER, S .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 140 (02) :735-742
[6]   STRUCTURE AND CONFORMATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT), AN INHIBITOR OF THE HIV (AIDS) VIRUS [J].
BIRNBAUM, GI ;
GIZIEWICZ, J ;
GABE, EJ ;
LIN, TS ;
PRUSOFF, WH .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1987, 65 (09) :2135-2139
[7]  
BIRNBAUM GI, 1987, TOPICS NUCLEIC ACI 3, P1
[8]   INITIAL STUDIES ON THE CELLULAR PHARMACOLOGY OF 2',3'-DIDEOXYCYTIDINE, AN INHIBITOR OF HTLV-III INFECTIVITY [J].
COONEY, DA ;
DALAL, M ;
MITSUYA, H ;
MCMAHON, JB ;
NADKARNI, M ;
BALZARINI, J ;
BRODER, S ;
JOHNS, DG .
BIOCHEMICAL PHARMACOLOGY, 1986, 35 (13) :2065-2068
[9]   THE QUEST FOR THERAPY [J].
DAGANI, R .
CHEMICAL & ENGINEERING NEWS, 1987, 65 (47) :41-49
[10]   BROAD-SPECTRUM ANTIRETROVIRAL ACTIVITY OF 2',3'-DIDEOXYNUCLEOSIDES [J].
DAHLBERG, JE ;
MITSUYA, H ;
BLAM, SB ;
BRODER, S ;
AARONSON, SA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (08) :2469-2473
123