INCREASED TURNOVER OF CEREBRAL NOREPINEPHRINE DURING REBOUND OF PARADOXICAL SLEEP IN RAT

被引:127
作者
PUJOL, JF
MOURET, J
JOUVET, M
GLOWINSKI, J
机构
[1] Unité de Neuropharmacologie Biochimique, Collège de France, Paris Ve
[2] Laboratoire de Pathologie Générale et Expérimentale, Faculté de Médecine, Lyon
[3] Unité de Neuropharmacologie Biochimique, Laboratoire de Neurophysiologie Générale
关键词
D O I
10.1126/science.159.3810.112
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Changes in turnover of cerebral norepinephrine, as measured after intracisternal administration of the H3 amine, have been studied in rats during selective paradoxical sleep deprivation and its following rebound. Experiments were performed under neurophysiological control. A marked increase of turnover of norepinephrine is associated with the augmentation of paradoxical sleep characteristic of the rebound period.
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页码:112 / +
页数:1
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