CATALYTIC FRIEDEL-CRAFTS ACYLATION REACTIONS USING HAFNIUM TRIFLATE AS A CATALYST IN LITHIUM PERCHLORATE-NITROMETHANE

被引：118

作者：

HACHIYA, I ^{[1
]}

MORIWAKI, M ^{[1
]}

KOBAYASHI, S ^{[1
]}

机构：

[1] SCI UNIV TOKYO,FAC SCI,DEPT APPL CHEM,SHINJUKU KU,TOKYO 162,JAPAN

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 03期

关键词：

D O I：

10.1016/0040-4039(94)02221-V

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Catalytic Friedel-Crafts acylation reactions were performed by using hafnium trifluoromethanesulfonate (hafnium triflate, Hf(OTf)(4)) as a catalyst. The catalytic activity of the Lewis acid catalyst was much improved in lithium perchlorate-nitromethane (LiClO4-MeNO(2)) and the yield was up to 250,000% based on the catalyst. Various substituted benzenes reacted with acid anhydrides in the presence of a catalytic amount of Hf(OTf)(4) to give the corresponding aromatic ketones in high yields.

引用

页码：409 / 412

页数：4