CONCISE SYNTHESIS OF A TAXOL A-RING SYNTHON - FORMATION OF A 1,2-ALKYLIDENE LINKAGE VIA ACETYLENE CHEMISTRY

被引：17

作者：

CRICH, D

CRICH, JZ

机构：

[1] Department of Chemistry, University of Illinois at Chicago (M/C 111), Chicago, Il 60607-7061

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 16期

关键词：

D O I：

10.1016/S0040-4039(00)77146-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A taxol A ring-synthon is obtained by oxidative cyclization of homogeranic acid with mercuric triflate followed by oxidative demercuration; the Meyer-Schuster rearrangement is then employed to form the highly sterically hindered taxol 1,2-bond.

引用

页码：2469 / 2472

页数：4

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