LOUISIANIN-A, LOUISIANIN-B, LOUISIANIN-C AND LOUISIANIN-D - NONSTEROIDAL GROWTH-INHIBITORS OF TESTOSTERONE-RESPONSIVE SC-115 CELLS .2. PHYSICOCHEMICAL PROPERTIES AND STRUCTURAL ELUCIDATION

被引：17

作者：

TAKAMATSU, S

KIM, YP

HAYASHI, M

FURUHATA, K

TAKAYANAGI, H

KOMIYAMA, K

WOODRUFF, HB

OMURA, S

机构：

[1] KITASATO INST,MINATO KU,TOKYO 108,JAPAN

[2] KITASATO UNIV,SCH PHARMACEUT SCI,MINATO KU,TOKYO 108,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1995年 / 48卷 / 10期

关键词：

D O I：

10.7164/antibiotics.48.1090

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

New non-steroidal growth inhibitors of testosterone-responsive SC 115 cells, louisianins A (MW: 189; C11H11NO2), B (MW: 191; C11H13NO2), C (MW: 173; C11H11NO) and D (MW: 173; C11H11NO) were isolated from the cultured broth of Streptomyces sp. WK-4028. Their structures were determined on the basis of spectroscopic data. The structure of louisianin A in particular was confirmed by X-ray crystallographic analysis. The four compounds commonly possess a unique pyrindine skeleton in the molecule.

引用

页码：1090 / 1094

页数：5

共 5 条

[1] 2-CYANO-1,3-DICARBONYL COMPOUNDS WITH ANTIALLERGIC ACTIVITY [J].