ASYMMETRIC AMPLIFICATION IN NICKEL-CATALYZED CONJUGATE ADDITION TO CHALCONE

被引：73

作者：

BOLM, C

机构：

[1] Department of Chemistry, University of Basel, CH-4056 Basel

来源：

TETRAHEDRON-ASYMMETRY | 1991年 / 2卷 / 07期

关键词：

D O I：

10.1016/S0957-4166(00)86124-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Nickel complexes with optically active pyridine ligands catalyze the conjugate addition of diethyl zinc to chalcone. This catalytic alkylation gives products with ee's of up to 86%. Strong asymmetric amplification has been observed using ligands of low optical purity.

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页码：701 / 704

页数：4

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