THE PRACTICAL MANAGEMENT OF MULTIPLE ENDOCRINE NEOPLASIA

被引：12

作者：

LEAROYD, DL

TWIGG, SM

MARSH, DJ

ROBINSON, BG

机构：

[1] ROYAL N SHORE HOSP, DEPT ENDOCRINOL, ST LEONARDS, NSW 2065, AUSTRALIA

[2] UNIV SYDNEY, SYDNEY, NSW 2006, AUSTRALIA

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1995年 / 6卷 / 08期

关键词：

D O I：

10.1016/1043-2760(95)00151-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Advances in the identification and localization of the abnormal genes in the multiple endocrine neoplasia syndromes have provided Mew methods of identifying ''at risk'' individuals in these families. Genetic testing using linkage analysis in multiple endocrine neoplasia (MEN) 1 and direct mutation analysis of the RET protooncogene in MEN 2 is MOW available for these disorders. New management issues for these disorders have resulted and a practical approach to these issues is discussed.

引用

收藏

页码：273 / 278

页数：6

相关论文

共 46 条

[21] A MUTATION IN THE RET PROTOONCOGENE ASSOCIATED WITH MULTIPLE ENDOCRINE NEOPLASIA TYPE-2B AND SPORADIC MEDULLARY-THYROID CARCINOMA [J].

HOFSTRA, RMW ;

LANDSVATER, RM ;

CECCHERINI, I ;

STULP, RP ;

STELWAGEN, T ;

LUO, Y ;

PASINI, B ;

HOPPENER, JWM ;

VANAMSTEL, HKP ;

ROMEO, G ;

LIPS, CJM ;

BUYS, CHCM .

NATURE, 1994, 367 (6461) :375-376

[22] PREDICTIVE TESTING FOR MULTIPLE ENDOCRINE NEOPLASIA TYPE-1 USING DNA POLYMORPHISMS [J].

LARSSON, C ;

SHEPHERD, J ;

NAKAMURA, Y ;

BLOMBERG, C ;

WEBER, G ;

WERELIUS, B ;

HAYWARD, N ;

TEH, B ;

TOKINO, T ;

SEIZINGER, B ;

SKOGSEID, B ;

OBERG, K ;

NORDENSKJOLD, M .

JOURNAL OF CLINICAL INVESTIGATION, 1992, 89 (04) :1344-1349

[23] LONG-TERM TREATMENT OF METASTATIC MEDULLARY-THYROID CARCINOMA WITH THE SOMATOSTATIN ANALOG OCTREOTIDE [J].

MAHLER, C ;

VERHELST, J ;

DELONGUEVILLE, M ;

HARRIS, A .

CLINICAL ENDOCRINOLOGY, 1990, 33 (02) :261-269

[24] A RAPID SCREENING METHOD FOR THE DETECTION OF MUTATIONS IN THE RET PROTOONCOGENE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE 2A AND FAMILIAL MEDULLARY-THYROID CARCINOMA FAMILIES [J].

MARSH, DJ ;

ROBINSON, BG ;

ANDREW, S ;

RICHARDSON, AL ;

POJER, R ;

SCHNITZLER, M ;

MULLIGAN, LM ;

HYLAND, VJ .

GENOMICS, 1994, 23 (02) :477-479

[25] FAMILIAL MULTIPLE ENDOCRINE NEOPLASIA TYPE-1 - MUTATION OF A TUMOR SUPPRESSOR GENE [J].

MARX, SJ .

TRENDS IN ENDOCRINOLOGY AND METABOLISM, 1989, 1 (02) :76-82

[26] PRIMARY HYPERPARATHYROIDISM - PREOPERATIVE LOCALIZATION USING TECHNETIUM SESTAMIBI SCANNING [J].

MITCHELL, BK ;

KINDER, BK ;

CORNELIUS, E ;

STEWART, AF .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1995, 80 (01) :7-10

[27] GERM-LINE MUTATIONS OF THE RET PROTOONCOGENE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE-2A [J].

MULLIGAN, LM ;

KWOK, JBJ ;

HEALEY, CS ;

ELSDON, MJ ;

ENG, C ;

GARDNER, E ;

LOVE, DR ;

MOLE, SE ;

MOORE, JK ;

PAPI, L ;

PONDER, MA ;

TELENIUS, H ;

TUNNACLIFFE, A ;

PONDER, BAJ .

NATURE, 1993, 363 (6428) :458-460

[28] SPECIFIC MUTATIONS OF THE RET PROTOONCOGENE ARE RELATED TO DISEASE PHENOTYPE IN MEN 2A AND FMTC [J].

MULLIGAN, LM ;

ENG, C ;

HEALEY, CS ;

CLAYTON, D ;

KWOK, JBJ ;

GARDNER, E ;

PONDER, MA ;

FRILLING, A ;

JACKSON, CE ;

LEHNERT, H ;

NEUMANN, HPH ;

THIBODEAU, SN ;

PONDER, BAJ .

NATURE GENETICS, 1994, 6 (01) :70-74

[29]

MULLIGAN LM, IN PRESS J INTERN ME

[30]

PONDER BAJ, 1988, LANCET, V1, P397

← 1 2 3 4 5 →