INTERNAL MOBILITY IN PHOSPHOLIPIDS

被引:33
作者
SHEARD, B
机构
[1] University Department of Physical Chemistry, Oxford
[2] Nuffield Department of Clinical Biochemistry, Radcliffe Infirmary
[3] Bell Telephone Laboratories Incorporated, Murray Hill, NJ
关键词
D O I
10.1038/2231057a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
WORK on optical birefringence1, X-ray diffraction2,3 and, with reservations, electron microscopy of stained and dried particles4,5 indicates that phospholipids in coarse aqueous dispersion, prepared by shaking the phospholipid with water, have a multi-lamellar structure composed of alternate layers of phospholipid and the solvent. The phospholipid lamellae are thought to be molecular bilayers with hydrophilic headgroups on both surfaces and hydrocarbon chains directed towards the centre. When finer dispersions are required it is customary to irradiate the course dispersion with ultrasound, and the purpose here is to comment on the changes which occur during this treatment. © 1969 Nature Publishing Group.
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页码:1057 / &
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