ACETOGENINS OF ANNONACEAE .24. COREPOXYLONE, A POSSIBLE PRECURSOR OF MONO-TETRAHYDROFURAN GAMMA-LACTONE ACETOGENINS - BIOMIMETIC SYNTHESIS OF COROSSOLONE

被引：31

作者：

GROMEK, D

FIGADERE, B

HOCQUEMILLER, R

CAVE, A

CORTES, D

机构：

[1] UNIV PARIS 11, FAC PHARM, CNRS, PHARMACOGNOSIE LAB, F-92290 CHATENAY MALABRY, FRANCE

[2] UNIV ROUEN, FAC MED & PHARM, PHARMACOGNOSIE LAB, F-76800 ST ETIENNE, FRANCE

来源：

TETRAHEDRON | 1993年 / 49卷 / 24期

关键词：

DIEPOXY ACETOGENINS; COREPOXYLONE; BIOMIMETIC SYNTHESIS; CYTOTOXICITY; ANNONA-MURICATA (ANNONACEAE);

D O I：

10.1016/S0040-4020(01)82374-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new diepoxy acetogenin with a carbonyl group, corepoxylone (1), has been isolated from the non-polar fractions of Annona muricata seeds. Its structure was elucidated on the basis of the spectral data, NMR and MS in particular. Biomimetic synthesis of corossolone (2)from (1) suggests its role in the biogenesis of mono-tetrahydrofuran acetogenins bearing a carbonyl group at C-10.

引用

页码：5247 / 5252

页数：6

共 15 条

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