CHARACTERIZATION OF A HOSPITAL OUTBREAK OF IMIPENEM-RESISTANT ACINETOBACTER-BAUMANNII BY PHENOTYPIC AND GENOTYPIC TYPING METHODS

被引：137

作者：

TANKOVIC, J ^{[1
]}

LEGRAND, P ^{[1
]}

DEGATINES, G ^{[1
]}

CHEMINEAU, V ^{[1
]}

BRUNBUISSON, C ^{[1
]}

DUVAL, J ^{[1
]}

机构：

[1] UNIV PARIS 12,HOP HENRI MONDOR,SERV REANIMAT MED,F-94010 CRETEIL,FRANCE

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1994年 / 32卷 / 11期

关键词：

D O I：

10.1128/JCM.32.11.2677-2681.1994

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

During a 13-month period, 31 patients hospitalized primarily in two intensive care units (ICUs) were either colonized or infected by imipenem-resistant Acinetobacter baumannii. Typing of the isolates by three methods (antibiotyping, biotyping, and pulsed-field gel electrophoresis) revealed that two distinct strains were involved in the first 9 cases of the outbreak and that one of these strains, which had acquired a higher level of imipenem resistance as well as resistance to all aminoglycosides, accounted for 21 of 22 cases in the second part of the outbreak. ICU environmental contamination was recognized as an important reservoir of this epidemic strain. The outbreak ceased only after the ICUs were closed for complete cleaning and disinfection.

引用

页码：2677 / 2681

页数：5

共 32 条

[21]

JOLYGUILLOU ML, 1990, PRESSE MED, V19, P357

[22] ESTERASE ELECTROPHORESIS COMPARED WITH BIOTYPING FOR EPIDEMIOLOGIC TYPING OF ACINETOBACTER-BAUMANNII STRAINS [J].

POUEDRAS, P ;

GRAS, S ;

SIRE, JM ;

MESNARD, R ;

DONNIO, PY ;

PICARD, B ;

AVRIL, JL .

FEMS MICROBIOLOGY LETTERS, 1992, 96 (2-3) :125-128

[23]

ROSENTHAL SL, 1974, AM J CLIN PATHOL, V62, P807

[24] AN OUTBREAK OF INFECTIONS WITH ACINETOBACTER-CALCOACETICUS IN BURN PATIENTS - CONTAMINATION OF PATIENTS MATTRESSES [J].

SHERERTZ, RJ ;

SULLIVAN, ML .

JOURNAL OF INFECTIOUS DISEASES, 1985, 151 (02) :252-258

[25]

STONE JW, 1985, J HOSP INFECT, V6, P42

[26] NOSOCOMIAL COLONIZATION AND INFECTION WITH MULTIRESISTANT ACINETOBACTER-BAUMANNII - OUTBREAK DELINEATION USING DNA MACRORESTRICTION ANALYSIS AND PCR-FINGERPRINTING [J].

STRUELENS, MJ ;

CARLIER, E ;

MAES, N ;

SERRUYS, E ;

QUINT, WGV ;

VANBELKUM, A .

JOURNAL OF HOSPITAL INFECTION, 1993, 25 (01) :15-32

[27]

TAPLIN D, 1963, JAMA-J AM MED ASSOC, V186, P952

[28] CLINICAL STRAINS OF ACINETOBACTER CLASSIFIED BY DNA-DNA HYBRIDIZATION [J].

TJERNBERG, I ;

URSING, J .

APMIS, 1989, 97 (07) :595-605

[29] ACINETOBACTER-BAUMANNII SEROTYPING FOR DELINEATION OF OUTBREAKS OF NOSOCOMIAL CROSS-INFECTION [J].

TRAUB, WH .

JOURNAL OF CLINICAL MICROBIOLOGY, 1989, 27 (12) :2713-2716

[30] EFFECT OF SULBACTAM ON INFECTIONS CAUSED BY IMIPENEM-RESISTANT ACINETOBACTER-CALCOACETICUS BIOTYPE ANITRATUS [J].

URBAN, C ;

GO, E ;

MARIANO, N ;

BERGER, BJ ;

AVRAHAM, I ;

RUBIN, D ;

RAHAL, JJ .

JOURNAL OF INFECTIOUS DISEASES, 1993, 167 (02) :448-451

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