BIDIFFRACTIVE GRATING COUPLER - UNIVERSAL TRANSDUCER FOR OPTICAL INTERFACE ANALYTICS

被引:26
作者
FATTINGER, C [1 ]
MANGOLD, C [1 ]
GALE, MT [1 ]
SCHUTZ, H [1 ]
机构
[1] PAUL SCHERRER INST,CH-8048 ZURICH,SWITZERLAND
关键词
INTEGRATED OPTICS; SENSORS; OPTICAL WAVE-GUIDES AND COUPLERS; SOLID-LIQUID INTERFACE; MONOLAYERS; REFRACTOMETRY;
D O I
10.1117/12.205680
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We report on a novel transducer devised for sensitive detection of the binding of molecules in the immediate vicinity of an optical surface, The transducer consists of a chip with a surface coated by an extremely thin waveguide film of amorphous TiO2 structured with a submicron grating relief. This microrelief is composed of two superimposed, uniform diffraction gratings of different periodicities, forming a bidiffractive grating with a frequency spectrum composed of two fundamental spatial harmonics. This bidiffractive grating serves as both an input and an output port for coupling and decoupling light beams to and from the planar waveguide. The bidiffractive coupler has translation-invariant coupling efficiency and allows background-free detection of the light decoupled from the waveguide. We outline the fabrication of the transducer and discuss the material properties of the waveguide film, which are very important for achieving optimum detection sensitivity, We assess the key factors affecting the detection limits of the transducer and comment on the resolution and the dynamic range for the measurement of changes in interfacial mass loading.
引用
收藏
页码:2744 / 2753
页数:10
相关论文
共 29 条
[1]  
BACH H, 1987, GLASTECH BER-GLASS, V60, P21
[2]  
BACH H, 1987, GLASTECH BER-GLASS, V60, P33
[3]   COMPARISON OF THE PROPERTIES OF TITANIUM-DIOXIDE FILMS PREPARED BY VARIOUS TECHNIQUES [J].
BENNETT, JM ;
PELLETIER, E ;
ALBRAND, G ;
BORGOGNO, JP ;
LAZARIDES, B ;
CARNIGLIA, CK ;
SCHMELL, RA ;
ALLEN, TH ;
TUTTLEHART, T ;
GUENTHER, KH ;
SAXER, A .
APPLIED OPTICS, 1989, 28 (16) :3303-3317
[4]   THE RESONANT MIRROR - A NOVEL OPTICAL SENSOR FOR DIRECT SENSING OF BIOMOLECULAR INTERACTIONS .2. APPLICATIONS [J].
BUCKLE, PE ;
DAVIES, RJ ;
KINNING, T ;
YEUNG, D ;
EDWARDS, PR ;
POLLARDKNIGHT, D ;
LOWE, CR .
BIOSENSORS & BIOELECTRONICS, 1993, 8 (7-8) :355-363
[5]   MEASUREMENTS OF ABSORPTION LOSSES IN TIO2 FILMS BY A COLLINEAR PHOTOTHERMAL DEFLECTION TECHNIQUE [J].
COMMANDRE, M ;
PELLETIER, E .
APPLIED OPTICS, 1990, 29 (28) :4276-4283
[6]   THE RESONANT MIRROR - A NOVEL OPTICAL BIOSENSOR FOR DIRECT SENSING OF BIOMOLECULAR INTERACTIONS .1. PRINCIPLE OF OPERATION AND ASSOCIATED INSTRUMENTATION [J].
CUSH, R ;
CRONIN, JM ;
STEWART, WJ ;
MAULE, CH ;
MOLLOY, J ;
GODDARD, NJ .
BIOSENSORS & BIOELECTRONICS, 1993, 8 (7-8) :347-353
[7]   THE DIFFERENCE INTERFEROMETER - A HIGHLY SENSITIVE OPTICAL PROBE FOR QUANTIFICATION OF MOLECULAR-SURFACE CONCENTRATION [J].
FATTINGER, C ;
KOLLER, H ;
SCHLATTER, D ;
WEHRLI, P .
BIOSENSORS & BIOELECTRONICS, 1993, 8 (02) :99-107
[8]   THE BIDIFFRACTIVE GRATING COUPLER [J].
FATTINGER, C .
APPLIED PHYSICS LETTERS, 1993, 62 (13) :1460-1462
[9]  
FATTINGER C, 1994, Patent No. 617273
[10]  
GRANZOW R, 1994, METHODS, V6, P93