CHIRAL ORGANOSILICON COMPOUNDS IN ASYMMETRIC-SYNTHESIS OF CHIRAL 1,3-DIOLS

被引：46

作者：

CHAN, TH

NWE, KT

机构：

[1] Department of Chemistry, McGill University, Quebec H3A 2K6, Montreal

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 23期

关键词：

D O I：

10.1021/jo00049a012

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral 1,3-diols can be prepared in high enantiomeric purity (>99% ee) from the reactions of the chiral silylcarbanion 2 with epoxides followed by oxidative cleavage of the carbon-silicon bond with hydrogen peroxide. The absolute configurations of some of the chiral 1,3-diols were determined by circular dichroism (CD).

引用

页码：6107 / 6111

页数：5

共 24 条

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