EXTRACTIVE FERMENTATION FOR LACTIC-ACID PRODUCTION

被引：147

作者：

YABANNAVAR, VM ^{[1
]}

WANG, DIC ^{[1
]}

机构：

[1] MIT, DEPT CHEM ENGN, CAMBRIDGE, MA 02139 USA

来源：

BIOTECHNOLOGY AND BIOENGINEERING | 1991年 / 37卷 / 11期

关键词：

EXTRACTIVE FERMENTATION; CELL IMMOBILIZATION; ALAMINE-336; PROCESS MODELING;

D O I：

10.1002/bit.260371115

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Lactic acid extractive fermentation was demonstrated using Alamine 336 in oleyl alcohol at acidic pH. The use of an efficient extraction system was possible through employment of the cell immobilization procedure. Process modeling was performed to relate the various process parameters such as flow rate, concentration, and pH. In experiments with 15% Alamine 336/oleyl alcohol, the bioreactor operation resulted in a higher productivity (12 g/L gel h) compared to that of a control fermentation (7 g/L gel h). Strategies for optimizing the extractive fermentation process were proposed considering both productivity and product recovery.

引用

页码：1095 / 1100

页数：6