ENANTIOSELECTIVE SYNTHESIS OF ALPHA-AMINO ACETALS AND ALPHA-AMINO-ACIDS BY NUCLEOPHILIC 1,2-ADDITION TO DIETHOXYACETALDEHYDE SAMP HYDRAZONE

被引：66

作者：

ENDERS, D ^{[1
]}

FUNK, R ^{[1
]}

KLATT, M ^{[1
]}

RAABE, G ^{[1
]}

HOVESTREYDT, ER ^{[1
]}

机构：

[1] SIEMENS AG,W-7500 KARLSRUHE 21,GERMANY

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1993年 / 32卷 / 03期

关键词：

D O I：

10.1002/anie.199304181

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The nucleophilic 1,2-addition of organocerium compounds to alpha-SAMP/RAMP hydrazone acetals 1 is the basis of a new, highly enantioselective route to synthetically versatile alpha-amino acetals 2 and alpha-amino acids 3. R = Me, Et, nPr, iPr, nBu, tBu, Ph. [GRAPHICS]

引用

页码：418 / 421

页数：4

共 59 条

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