A RAPID TOTAL SYNTHESIS OF AN ELLAGITANNIN

被引：97

作者：

NELSON, TD ^{[1
]}

MEYERS, AI ^{[1
]}

机构：

[1] COLORADO STATE UNIV, DEPT CHEM, FT COLLINS, CO 80523 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 09期

关键词：

D O I：

10.1021/jo00088a046

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ellagitannins are galloyl esters of glucose that contain at least one chiral biaryl (digalloyl) subunit. Included in this family are the tellimagrandins (1-3). The first asymmetric synthesis of (S)-4,4',5,5',6,6'-hexamethoxy-2,2'-diphenic acid, a ubiquitous subunit in ellagitannins, is reported by utilization of an intermolecular oxazoline-mediated asymmetric Ullmann coupling. Attachment of this acid to an appropriate glucose core resulted in the synthesis of an ellagitannin.

引用

页码：2577 / 2580

页数：4

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