NORMAL HUMAN TISSUES CONTAIN RNA AND ANTIGENS RELATED TO INFECTIOUS ADENOVIRUS TYPE-2

被引：29

作者：

JONES, KW ^{[1
]}

KINROSS, J ^{[1
]}

MAITLAND, N ^{[1
]}

NORVAL, M ^{[1
]}

机构：

[1] UNIV EDINBURGH,SCH MED,DEPT BACTERIOL,EDINBURGH EH8 9YL,MIDLOTHIAN,SCOTLAND

来源：

NATURE | 1979年 / 277卷 / 5694期

关键词：

D O I：

10.1038/277274a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Normal human tissues have been found to contain RNA which hybridises with four regions of the adenovirus type 2 genome, including one which contains the transforming gene(s) of this virus. The RNAs have also been extracted from gorilla organs, but not from those of chickens, suggesting that they are a feature of all normal higher primate tissues. Serological tests suggest that these homologous RNAs are translated into proteins connected with essentially normal and virus-infected cell functions. © 1979 Nature Publishing Group.

引用

页码：274 / 279

页数：6

共 31 条

[11] HILLEMAN MR, 1954, P SOC EXP BIOL MED, V85, P183, DOI 10.3181/00379727-85-20825
[12] SPECIFIC ADENOVIRUS COMPLEMENT-FIXING ANTIGENS IN VIRUS-FREE HAMSTER AND RAT TUMORS
HUEBNER, RJ
ROWE, WP
TURNER, HC
LANE, WT
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1963, 50 (02) : 379 - &
[13] DETECTION OF MYOSIN HEAVY-CHAIN MESSENGER-RNA DURING MYOGENESIS IN TISSUE-CULTURE BY INVITRO AND INSITU HYBRIDIZATION
JOHN, HA
PATRINOUGEORGOULAS, M
JONES, KW
[J]. CELL, 1977, 12 (02) : 501 - 508
[14] JONES KW, 1978, ONCOGENESIS HERPES V, V3
[15] ISOLATION OF DELETION AND SUBSTITUTION MUTANTS OF ADENOVIRUS TYPE-5
JONES, N
SHENK, T
[J]. CELL, 1978, 13 (01) : 181 - 188
[16] ANTIGENIC SIMILARITY BETWEEN SIMIAN-VIRUS 40-INDUCED SURFACE AND FETAL ANTIGENS IN HAMSTER CELLS
KATO, K
[J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1977, 58 (02) : 259 - 262
[17] KLEIN G, 1973, HERPESVIRUSES, pCH16
[18] 2 ADENOVIRUS MESSENGER-RNAS HAVE A COMMON 5' TERMINAL LEADER SEQUENCE ENCODED AT LEAST 10 KB UPSTREAM FROM THEIR MAIN CODING REGIONS
KLESSIG, DF
[J]. CELL, 1977, 12 (01) : 9 - 21
[19] BIOCHEMICAL STUDIES ON ADENOVIRUS MULTIPLICATION .13. SYNTHESIS OF VIRUS-SPECIFIC RIBONUCLEIC ACID DURING INFECTION WITH HUMAN ADENOVIRUS TYPE 12
MAK, S
GREEN, M
[J]. JOURNAL OF VIROLOGY, 1968, 2 (10) : 1055 - &
[20] DETECTION OF VIRUS-SPECIFIC DNA AND RNA BASE-SEQUENCES IN INDIVIDUAL CELLS TRANSFORMED OR INFECTED BY ADENOVIRUS TYPE-2
MOAR, MH
JONES, KW
[J]. INTERNATIONAL JOURNAL OF CANCER, 1975, 16 (06) : 998 - 1007

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