METABOLISM OF 2-AMINOETHYLPHOSPHONATE LIPIDS IN TETRAHYMENA PYRIFORMIS

被引：64

作者：

THOMPSON, GA

机构：

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1969年 / 176卷 / 02期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0005-2760(69)90191-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The rapid incorporation of [14C]palmitic acid or [3H]chimyl alcohol into the choline phospholipids of Tetrahymena pyriformis is followed by a gradual transfer of the labeled glyceride moiety from that fraction to 2-aminoethylphosphonate or its precursor. Thus it appears that choline phosphatide is the lipid participant postulated to take part in carbon-phosphorus bond formation. The phosphonolipids, once formed, resist attack by endogenous lipolytic enzymes of Tetrahymena. The phosphonolipids and the structurally similar lipid, phosphatidylethanolamine, are therefore synthesized and degraded at rates which differ markedly. © 1969.

引用

页码：330 / &

共 18 条

[1]

BARTLETT GR, 1959, J BIOL CHEM, V234, P466

[2]

BLIGH EG, 1959, CAN J BIOCHEM PHYS, V37, P911

[3] SYNCHRONOUS DIVISIONS IN TETRAHYMENA-PYRIFORMIS AS STUDIED IN AN INORGANIC MEDIUM - THE EFFECT OF 2,4-DINITROPHENOL [J].