PANCREATIC RESECTION FOR DUCTAL ADENOCARCINOMA - TOTAL PANCREATECTOMY VERSUS PARTIAL PANCREATECTOMY

被引：4

作者：

FARLEY, DR ^{[1
]}

SARR, MG ^{[1
]}

VANHEERDEN, JA ^{[1
]}

机构：

[1] MAYO CLIN & MAYO FDN,DEPT SURG,200 1ST ST SW,ROCHESTER,MN 55905

来源：

SEMINARS IN SURGICAL ONCOLOGY | 1995年 / 11卷 / 02期

关键词：

DUCTAL ADENOCARCINOMA; PANCREATIC HEAD; TOTAL PANCREATECTOMY; PARTIAL PANCREATECTOMY;

D O I：

10.1002/ssu.2980110209

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The controversy regarding total versus partial pancreatectomy for ductal adenocarcinoma of the pancreatic head remains unsettled. Proponents of total pancreatectomy claim wider margins of resection, avoidance of a troublesome pancreaticoenterostomy, and removal of a potentially multicentric disease. Advocates of partial pancreatectomy highlight the retention of exocrine and endocrine pancreatic function, the maintenance of splenic function, and a lower risk of marginal ulceration without sacrificing curative potential. Analysis of the current surgical literature with focus on the facets of each procedure that may differ (operative mortality, long-term survival, and the six factors mentioned above), may help to resolve the controversy. The data reviewed would suggest that 1) wider resection margins have not transferred into longer postoperative survival, 2) the risk of multicentricity is probably low and of questionable significance, and 3) the morbidity and mortality of pancreaticoenterostomy is currently less problematic. The additional benefits of retaining pancreatic endocrine and exocrine function, maintaining splenic immune competence, and a lower risk of marginal ulceration convinces us to advocate partial pancreatectomy over total pancreatectomy for the majority of patients with a resectable ductal adenocarcinoma of the pancreatic head. (C) 1995 Wiley-Liss, Inc.

引用

页码：124 / 131

页数：8

共 74 条

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