BINDING OF NUCLEOTIDES IN WATER BY PHENANTHRIDINIUM BIS(INTERCALAND) RECEPTOR MOLECULES

被引:77
作者
CUDIC, P
ZINIC, M
TOMISIC, V
SIMEON, V
VIGNERON, JP
LEHN, JM
机构
[1] RUDJER BOSKOVIC INST, DEPT ORGAN & BIOCHEM, SUPRAMOLEC & NUCLEOSIDE CHEM LAB, ZAGREB 41000, CROATIA
[2] UNIV ZAGREB, FAC SCI, CHEM PHYS LAB, ZAGREB, CROATIA
[3] COLL FRANCE, F-75005 PARIS, FRANCE
关键词
D O I
10.1039/c39950001073
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The bis(phenanthridinium) receptor molecules 3-5 bind nucleotides in aqueous media by stacking interactions between cis-oriented receptor units and the intercalated nucleic base part of a nucleotide with stability constants in the range 10(5)-10(6) dma mol(-1), the highest measured to date for these type of receptors and substrates.
引用
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页码:1073 / 1075
页数:3
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