ORGANOPHOSPHORUS COMPOUNDS .8. DIPHENYLPHOSPHINOTHIOIC ACID DERIVATIVES AS REAGENTS FOR PROTEINS

被引：13

作者：

SPENCE, RA

SWAN, JM

WRIGHT, SHB

机构：

[1] Department of Chemistry, Monash University, Clayton, VIC

[2] Department of Pathology, Monash Medical School, Prahran, VIC

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 1969年 / 22卷 / 11期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1071/CH9692359

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Esters and other derivatives of diphenylphosphinothioic acids are examined as potential agents for the radioactive labelling of immunoglobulins and other proteins. Syntheses, model reactions with amines, and mass spectra of the organo-phosphorus compounds are discussed. The labelling of immunoglobulins by reaction with [32P]diphenylphosphinothioic chloride, with [32P]diphenylphosphinothioic isothiocyanate, and with [32P]diphenylphosphinodithioic acid in the presence of condensing agents such as dimethylcyanamide and carbodiimides is reported. © 1969, CSIRO. All rights reserved.

引用

页码：2359 / &

共 13 条

[1]

BALDWIN RA, 1966, J ORG CHEM, V30, P3860

[2] MASS SPECTROMETRIC STUDIES .3. BIS(DIPHENYLAMINO)METHANE BIS(DIPHENYLPHOSPHINO)METHANE BIS(DIPHENYLARSINO)METHANE AND RELATED COMPOUNDS [J].