GALACTOSE BIOSENSORS USING COMPOSITE POLYMERS TO PREVENT INTERFERENCES

被引：69

作者：

MANOWITZ, P ^{[1
]}

STOECKER, PW ^{[1
]}

YACYNYCH, AM ^{[1
]}

机构：

[1] RUTGERS STATE UNIV,DEPT CHEM,NEW BRUNSWICK,NJ 08903

来源：

BIOSENSORS & BIOELECTRONICS | 1995年 / 10卷 / 3-4期

关键词：

BIOSENSOR; COMPOSITE POLYMER; NAFION; 1,3-PHENYLENEDIAMINE; ELECTROPOLYMERIZATION; GALACTOSE; 1,3-DIAMINOBENZENE; GALACTOSE OXIDASE; INTERFERENCES;

D O I：

10.1016/0956-5663(95)96854-R

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A biosensor using a composite polymer to prevent interferences was used in a flow injection analysis system for the detection of galactose in human plasma. The biosensor consisted of galactose oxidase immobilized on a platinized carbon electrode that had been modified with a composite polymer. The composite polymer showed improved selectivity to hydrogen peroxide compared with either of its individual polymeric components, Nafion and a copolymer of diaminobenzene and resorcinol. The composite polymer minimized the effect of possible interference from urate, ascorbate, and acetaminophen. This analytical system had a minimum detection limit of 50 mu M, linearity to 6 mM, a storage stability of greater than 30 days, and a high sample throughput (approx. 120 samples/h).

引用

页码：359 / 370

页数：12

共 27 条

[1] A NEW GLUCOSE SENSOR MADE OF A NAFION-GEL-LAYER COVERED CARBON-PASTE [J].