A COMPARISON OF SUTURE AND TUBULIZATION NERVE REPAIR TECHNIQUES IN A PRIMATE

被引:39
作者
HENTZ, VR [1 ]
ROSEN, JM [1 ]
XIAO, SJ [1 ]
MCGILL, KC [1 ]
ABRAHAM, G [1 ]
机构
[1] DEPT SURG,STANFORD,CA
来源
JOURNAL OF HAND SURGERY-AMERICAN VOLUME | 1991年 / 16A卷 / 02期
关键词
D O I
10.1016/S0363-5023(10)80106-6
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
This study compared standard methods of nerve repair, epineurial or perineurial sutures with a technique termed fascicular tubulization using a biodegradable polyglycolic acid tube in a nonhuman primate model. Electrophysiologic analysis demonstrated that the percentage of proximal axons that conducted across the repair site did not significantly differ among the three techniques while epineurial suture repairs were associated with significantly longer conduction delays across the repair site compared with the other two techniques. Even though fascicular tubulization using the current polyglycolic acid tube resulted in regeneration equal to the currently perceived best suture repair technique, associated technical problems with the current tube design indicate that this fascicular tubulization technique cannot, at present, be considered as an alternative to present clinically used nerve suture techniques.
引用
收藏
页码:251 / 261
页数:11
相关论文
共 41 条
[31]  
Gibby WA, Loerber HR, Horch KW, A quantitative evaluation of suture and tubulization nerve repair techniques, J Neurosurg, 58, pp. 574-579, (1983)
[32]  
Breidenbach WB, Terzis JK, The blood supply of vaclarized nerve grafts, J Reconstr Microsurg, 3, (1986)
[33]  
Brushart TM, Tarlov E, Mesulam MM, A comparison of motor neuron pool organization after epineurial and perineurial repair of the rat sciatic nerve, Orthrop Trans, 4, pp. 19-20, (1980)
[34]  
Brushart TM, Seiler WA, Selective reinnervation of distal motor stumps by peripheral motor axons, Exp Neurol, 97, pp. 289-300, (1987)
[35]  
Edshage S, Niebauer JJ, Evaluation of freezing as a method to improve cut surfaces in peripheral nerves preparatory to suturing, Plast Reconstr Surg, 37, pp. 196-202, (1966)
[36]  
Mira JC, Effects of repeated experimental localized freezings in the distal stump of peripheral nerve, Clin Plast Surg, 11, pp. 17-26, (1984)
[37]  
Fields RD, Le Beau JM, Longo FM, Ellisman MH, Nerve regeneration through artificial tubular implants, Prog Neurobiol, 33, pp. 87-134, (1989)
[38]  
Lundborg G, Dahlin LB, Danielson N, Et al., Nerve regeneration across an extended gap: a neurobiological review of nerve repair and the possible involvement of neuronotrophic factors, J Hand Surg, 7, (1982)
[39]  
Mackinnon SE, Dellon AL, Lundborg G, Hudson AR, A study of neurotropism in the primate model, J Hand Surg, 11 A, pp. 888-894, (1986)
[40]  
Politis MJ, Ederle K, Spencer PS, Tropism in nerve regeneration in vivo: Attraction of regenerating axons by diffusible factors derived from cells in distal nerve stumps of transected peripheral nerves, Brain Res, 253, pp. 1-12, (1982)