Biosynthetic studies of ecteinascidins in the marine tunicate Ecteinascidia turbinata

被引：17

作者：

Kerr, RG

Miranda, NF

机构：

[1] Department of Chemistry, Florida Atlantic University, Boca Raton

来源：

JOURNAL OF NATURAL PRODUCTS | 1995年 / 58卷 / 10期

关键词：

D O I：

10.1021/np50124a025

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A viable cell-free extract of the marine tunicate Ecteinascidia turbinata has been generated that is capable of transforming amino acids into the ecteinascidin antitumor alkaloids. Tyrosine and cysteine were identified as two building blocks used in ecteinascidin production. The enzyme preparations in the in vitro studies were fortified with ATP, Mg2+, NADH, and NADPH.

引用

页码：1618 / 1621

页数：4

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