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REGULATION OF NA+,K+-ATPASE GENE-EXPRESSION - A MODEL TO STUDY TERMINAL DIFFERENTIATION

被引：9
作者：
CELSI, G
WANG, ZM
机构：
[1] Department of Paediatrics, St. Göran's Children's Hospitals, Karolinska Institutet, Stockholm
来源：
PEDIATRIC NEPHROLOGY | 1993年 / 7卷 / 05期
关键词：
NA+; K+-ATPASE EXPRESSION; TRANSCRIPTIONAL REGULATION; GLUCOCORTICOIDS; THYROXINE;
D O I：
10.1007/BF00852570
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
This review focuses on the ontogeny of factors involved in the transcriptional regulation of Na+,K+-ATPase expression. The Na+,K+-ATPase enzyme is of vital importance for cell function. It is likely that the limited availability of Na+,K+-ATPase in infant tissue is the major limiting factor for adaptation to extra-uterine life in several organs. The factors regulating Na+,K+-ATPase gene transcription in infancy are discussed. Special emphasis is given to the role of circulating hormones such as glucocorticoids and thyroxine.
引用
收藏
页码：630 / 634
页数：5
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