REGULATION OF NA+,K+-ATPASE GENE-EXPRESSION - A MODEL TO STUDY TERMINAL DIFFERENTIATION

被引：9

作者：

CELSI, G

WANG, ZM

机构：

[1] Department of Paediatrics, St. Göran's Children's Hospitals, Karolinska Institutet, Stockholm

来源：

PEDIATRIC NEPHROLOGY | 1993年 / 7卷 / 05期

关键词：

NA+; K+-ATPASE EXPRESSION; TRANSCRIPTIONAL REGULATION; GLUCOCORTICOIDS; THYROXINE;

D O I：

10.1007/BF00852570

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

This review focuses on the ontogeny of factors involved in the transcriptional regulation of Na+,K+-ATPase expression. The Na+,K+-ATPase enzyme is of vital importance for cell function. It is likely that the limited availability of Na+,K+-ATPase in infant tissue is the major limiting factor for adaptation to extra-uterine life in several organs. The factors regulating Na+,K+-ATPase gene transcription in infancy are discussed. Special emphasis is given to the role of circulating hormones such as glucocorticoids and thyroxine.

引用

页码：630 / 634

页数：5

共 69 条

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