NUCLEOTIDE-SEQUENCE AND FUNCTIONS OF MRK DETERMINANTS NECESSARY FOR EXPRESSION OF TYPE-3 FIMBRIAE IN KLEBSIELLA-PNEUMONIAE

被引:94
作者
ALLEN, BL
GERLACH, GF
CLEGG, S
机构
[1] UNIV IOWA,DEPT MICROBIOL,IOWA CITY,IA 52242
[2] UNIV SASKATCHEWAN,VET INFECT DIS ORG,SASKATOON S7N 0W0,SASKATCHEWAN,CANADA
关键词
D O I
10.1128/jb.173.2.916-920.1991
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The nucleotide sequence of six genes involved in the expression of type 3 fimbriae of Klebsiella pneumoniae was determined. In addition to the genes that encode the fimbrial subunit (mrkA) and adhesin (mrkD), the mrkB, mrkC, and mrkE genes appear to be involved in assembly of the fimbrial filament and regulation of type 3 fimbrial expression. The mrkF gene product is required to maintain the stability of the fimbrial filament on the cell surface.
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页码:916 / 920
页数:5
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