ELECTRODIALYTIC SAMPLE TREATMENT COUPLED ONLINE WITH HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：30

作者：

DEBETS, AJJ

KOK, WT

HUPE, KP

BRINKMAN, UAT

机构：

[1] FREE UNIV AMSTERDAM,DEPT ANALYT CHEM,DE BOELELAAN 1083,1081 HV AMSTERDAM,NETHERLANDS

[2] UNIV AMSTERDAM,ANALYT CHEM LAB,1018 WV AMSTERDAM,NETHERLANDS

来源：

CHROMATOGRAPHIA | 1990年 / 30卷 / 7-8期

关键词：

Column liquid chromatography; Electrodialytic sample treatment; On-line coupling;

D O I：

10.1007/BF02328498

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An electrodialytic sample treatment method coupled on-line with high-performance liquid chromatography (EDIST-HPLC) is discussed in this paper. The performance of EDIST as a function of the donor-phase (sample solution) flow rate, the voltage applied over the electrodialysis block, and the time of dialysis has been studied using the basic drug ephedrine as a model compound. Enrichment of the analyte by a factor of 10-20 was possible. The determination of human plasma spiked with ephedrine is briefly discussed. © 1990 Friedr. Vieweg & Sohn Verlagsgesellschaft mbH.

引用

页码：361 / 366

页数：6

共 18 条

[1] MONITORING OF VETERINARY DRUG RESIDUES BY A COMBINATION OF CONTINUOUS-FLOW TECHNIQUES AND COLUMN-SWITCHING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY .1. SULFONAMIDES IN EGG, MEAT AND MILK USING POST-COLUMN DERIVATIZATION WITH DIMETHYLAMINOBENZALDEHYDE [J].