APPLICATION OF THE 3-DIMENSIONAL STRUCTURES OF PROTEIN TARGET MOLECULES IN STRUCTURE-BASED DRUG DESIGN

[1] INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE BY A C2-SYMMETRICAL PHOSPHINATE - SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS [J]. BIOCHEMISTRY, 1993, 32 (31) : 7972 - 7980

[2] ABRAHAM DJ, 1989, COMPUTER AIDED DRUG, P93

[3] ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE-II [J]. BIOCHEMISTRY, 1991, 30 (46) : 11064 - 11072

[4] DESIGN OF ENZYME-INHIBITORS USING ITERATIVE PROTEIN CRYSTALLOGRAPHIC ANALYSIS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (07) : 1925 - 1934

[5] Appelt Krzysztof, 1993, Perspectives in Drug Discovery and Design, V1, P23, DOI 10.1007/BF02171654

[6] THIENOTHIOPYRAN-2-SULFONAMIDES - NOVEL TOPICALLY ACTIVE CARBONIC-ANHYDRASE INHIBITORS FOR THE TREATMENT OF GLAUCOMA [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (12) : 2510 - 2513

[7] Bartlett PA, 1989, MOL RECOGNITION CHEM, V78, P182

[8] SYMMETRY IN PROSTAGLANDINS [J]. PROSTAGLANDINS, 1977, 13 (03): : 493 - 502

[9] FINE TUNING OF THE CATALYTIC PROPERTIES OF CARBONIC-ANHYDRASE - STUDIES OF A THR200-] HIS VARIANT OF HUMAN ISOENZYME-II [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1990, 190 (02): : 351 - 357

[10] PROTEIN DATA BANK - COMPUTER-BASED ARCHIVAL FILE FOR MACROMOLECULAR STRUCTURES [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1978, 185 (02) : 584 - 591

[1] INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE BY A C2-SYMMETRICAL PHOSPHINATE - SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS [J]. BIOCHEMISTRY, 1993, 32 (31) : 7972 - 7980

[2] ABRAHAM DJ, 1989, COMPUTER AIDED DRUG, P93

[3] ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE-II [J]. BIOCHEMISTRY, 1991, 30 (46) : 11064 - 11072

[4] DESIGN OF ENZYME-INHIBITORS USING ITERATIVE PROTEIN CRYSTALLOGRAPHIC ANALYSIS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (07) : 1925 - 1934

[5] Appelt Krzysztof, 1993, Perspectives in Drug Discovery and Design, V1, P23, DOI 10.1007/BF02171654

[6] THIENOTHIOPYRAN-2-SULFONAMIDES - NOVEL TOPICALLY ACTIVE CARBONIC-ANHYDRASE INHIBITORS FOR THE TREATMENT OF GLAUCOMA [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (12) : 2510 - 2513

[7] Bartlett PA, 1989, MOL RECOGNITION CHEM, V78, P182

[8] SYMMETRY IN PROSTAGLANDINS [J]. PROSTAGLANDINS, 1977, 13 (03): : 493 - 502

[9] FINE TUNING OF THE CATALYTIC PROPERTIES OF CARBONIC-ANHYDRASE - STUDIES OF A THR200-] HIS VARIANT OF HUMAN ISOENZYME-II [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1990, 190 (02): : 351 - 357

[10] PROTEIN DATA BANK - COMPUTER-BASED ARCHIVAL FILE FOR MACROMOLECULAR STRUCTURES [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1978, 185 (02) : 584 - 591