TRANSDERMAL FENTANYL USE IN HOSPICE HOME-CARE PATIENTS WITH CHRONIC CANCER PAIN

被引：23

作者：

HERBST, LH ^{[1
]}

STRAUSE, LG ^{[1
]}

机构：

[1] SAN DIEGO HOSPICE,4311 3RD AVE,SAN DIEGO,CA 92103

来源：

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT | 1992年 / 7卷 / 03期

关键词：

CANCER; PAIN MANAGEMENT; FENTANYL; TRANSDERMAL; HOSPICE;

D O I：

10.1016/0885-3924(92)90056-N

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

In this study, 11 cancer patients who experienced severe pain were treated with transdermal fentanyl. Of the 11 patients, 7 completed the 4-wk protocol. Of the 4 patients who did not complete the study, 3 died due to disease progression, and 1 was withdrawn by the primary physician. Patients' pain level, mood, and quality of life were evaluated before starting the transdermal fentanyl patch system and again at 2 and 4 wk. Data from the 7 patients who completed the study showed no statistical differences in pain level, mood, or quality of life at any of the three time points. Starting doses ranged from 25-mu-g/hr to 325-mu-g/hr, with increases from 0% to 300%. There were no significant adverse reactions to the medication. The hospice patients chose to continue with the transdermal fentanyl system for pain control after completing the study.

引用

页码：S54 / S57

页数：4

共 17 条

[11]

Gourlay, Kowalski, Plummer, Et al., The efficacy of transdermal fentanyl in the treatment of postoperative pain: a double-blind comparison of fentanyl and placebo systems, Pain, 40, pp. 21-28, (1990)

[12]

Miser, Narang, Dothage, Young, Sindelar, Miser, Transdermal fentanyl for pain control in patients with cancer, Pain, 37, pp. 15-21, (1989)

[13]

Food and Drug Administration, Fentanyl transdermal system approved for chronic pain, JAMA, 264, (1990)

[14]

Huskisson, Measurement of pain, Lancet, 9, pp. 1127-1131, (1974)

[15]

Schipper, Levitt, Quality of life in cancer trials: what is it: why measure it?, Assessment of quality of life and cancer treatment, pp. 19-29, (1986)

[16]

Rosow, Moss, Philbin, Savarese, Histamine release during morphine and fentanyl anesthesia, Anesthesiology, 56, pp. 93-96, (1982)

[17]

Shaw, Chandrasekaran, Transdermal therapeutic systems, Drug absorption. Proceedings of the International Conference on Drug Absorption, pp. 186-193, (1985)

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