HIGH-PERFORMANCE CAPILLARY ELECTROPHORESIS

被引：20

作者：

FRENZ, J

HANCOCK, WS

机构：

[1] J. Frenz and W. S. Hancock are, the Department of Medicinal and Analytical Chemistry, Genentech, Inc., South Francisco, CA 94080

来源：

TRENDS IN BIOTECHNOLOGY | 1991年 / 9卷 / 07期

关键词：

D O I：

10.1016/0167-7799(91)90078-V

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The application of recombinant-DNA methods for the production of therapeutic proteins has, over the past decade, driven the development of new technology for the analysis and characterization of biological molecules. High performance capillary electrophoresis (HPCE) has generated enormous interest among biochemists, analytical chemists and chromatographers, and is emerging as an extremely high-resolution separation technique, that may rival high performance liquid chromatography (HPLC) in its efficiency and breadth of application.

引用

页码：243 / 250

页数：8

共 30 条

[1]

BRENNAN T, 1990, BIOLOGICAL MASS SPECTROMETRY /, P159

[2] HIGH-PERFORMANCE SODIUM DODECYL-SULFATE POLYACRYLAMIDE-GEL CAPILLARY ELECTROPHORESIS OF PEPTIDES AND PROTEINS [J].

COHEN, AS ;

KARGER, BL .

JOURNAL OF CHROMATOGRAPHY, 1987, 397 :409-417

[3] SEPARATION AND ANALYSIS OF DNA-SEQUENCE REACTION-PRODUCTS BY CAPILLARY GEL-ELECTROPHORESIS [J].

COHEN, AS ;

NAJARIAN, DR ;

KARGER, BL .

JOURNAL OF CHROMATOGRAPHY, 1990, 516 (01) :49-60

[4] HIGH-SPEED SEPARATIONS OF DNA SEQUENCING REACTIONS BY CAPILLARY ELECTROPHORESIS [J].

DROSSMAN, H ;

LUCKEY, JA ;

KOSTICHKA, AJ ;

DCUNHA, J ;

SMITH, LM .

ANALYTICAL CHEMISTRY, 1990, 62 (09) :900-903

[5] CAPILLARY ELECTROPHORESIS [J].

EWING, AG ;

WALLINGFORD, RA ;

OLEFIROWICZ, TM .

ANALYTICAL CHEMISTRY, 1989, 61 (04) :A292-+

[6] CHARACTERIZATION OF HUMAN GROWTH-HORMONE BY CAPILLARY ELECTROPHORESIS [J].

FRENZ, J ;

WU, SL ;

HANCOCK, WS .

JOURNAL OF CHROMATOGRAPHY, 1989, 480 :379-391

[7]

FRENZ J, 1989, HPLC ADV PERSPECTIVE, V5, P212

[8]

FRENZ J, 1990, PEPTIDES CHEM STRUCT, P430

[9] ELECTROKINETIC RESOLUTION OF AMINO-ACID ENANTIOMERS WITH COPPER(II) ASPARTAME SUPPORT ELECTROLYTE [J].

GOZEL, P ;

GASSMANN, E ;

MICHELSEN, H ;

ZARE, RN .

ANALYTICAL CHEMISTRY, 1987, 59 (01) :44-49

[10] SEPARATION OF DNA RESTRICTION FRAGMENTS BY HIGH-PERFORMANCE CAPILLARY ELECTROPHORESIS WITH LOW AND ZERO CROSS-LINKED POLYACRYLAMIDE USING CONTINUOUS AND PULSED ELECTRIC-FIELDS [J].

HEIGER, DN ;

COHEN, AS ;

KARGER, BL .

JOURNAL OF CHROMATOGRAPHY, 1990, 516 (01) :33-48

← 1 2 3 →