POSITRON EMISSION TOMOGRAPHY - A NEW TECHNIQUE FOR STUDIES OF THE CENTRAL-NERVOUS-SYSTEM

被引：12

作者：

ERIKSSON, L

DAHLBOM, M

WIDEN, L

机构：

[1] KAROLINSKA INST,DEPT NEURORADIOL,S-10401 STOCKHOLM 60,SWEDEN

[2] KAROLINSKA INST,DEPT RADIAT PHYS,S-10401 STOCKHOLM 60,SWEDEN

[3] KAROLINSKA HOSP,S-10401 STOCKHOLM 60,SWEDEN

来源：

JOURNAL OF MICROSCOPY-OXFORD | 1990年 / 157卷

关键词：

brain imaging; brain studies; central nervous system; positron camera; Positron emission tomography;

D O I：

10.1111/j.1365-2818.1990.tb02968.x

中图分类号：

TH742 [显微镜];

学科分类号：

摘要：

Positron emission tomography (PET) has become an important tool to study the central nervous system. Examples of such studies are cerebral blood flow and metabolism and determination of receptor characteristics of the brain. In the following the basic principles and the physics behind PET are given. Different aspects are discussed such as detector design, image reconstructions and data analyses. Since quantification is essential in PET, data have to be corrected for absorption, scatter and random coincidences. These corrections and their influence on image data are discussed. A review of state‐of‐the‐art PET research of the brain is given. 1990 Blackwell Science Ltd

引用

页码：305 / 333

页数：29

共 62 条

[51]

PHELPS ME, 1975, J NUCL MED, V16, P210

[52]

PHELPS ME, 1986, POSITRON EMISSION TO

[53] [FLUORODEOXYGLUCOSE-F-18 METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE-UTILIZATION IN MAN [J].

REIVICH, M ;

KUHL, D ;

WOLF, A ;

GREENBERG, J ;

PHELPS, M ;

IDO, T ;

CASELLA, V ;

FOWLER, J ;

HOFFMAN, E ;

ALAVI, A ;

SOM, P ;

SOKOLOFF, L .

CIRCULATION RESEARCH, 1979, 44 (01) :127-137

[54]

ROLAND P, 1989, WENNERGREN CTR INT S, V53

[55]

ROLAND PE, 1987, J NEUROSCI, V7, P2373

[56] INVIVO DEMONSTRATION OF REDUCED BENZODIAZEPINE RECEPTOR-BINDING IN HUMAN EPILEPTIC FOCI [J].

SAVIC, I ;

ROLAND, P ;

SEDVALL, G ;

PERSSON, A ;

PAULI, S ;

WIDEN, L .

LANCET, 1988, 2 (8616) :863-866

[57] METABOLIC MAPPING OF FUNCTIONAL-ACTIVITY IN THE HYPOTHALAMO-NEUROHYPOPHYSEAL SYSTEM OF THE RAT [J].

SCHWARTZ, WJ ;

SMITH, CB ;

DAVIDSEN, L ;

SAVAKI, H ;

SOKOLOFF, L ;

MATA, M ;

FINK, DJ ;

GAINER, H .

SCIENCE, 1979, 205 (4407) :723-725

[58] [DEOXYGLUCOSE-C-14 METHOD FOR MEASUREMENT OF LOCAL CEREBRAL GLUCOSE-UTILIZATION - THEORY, PROCEDURE, AND NORMAL VALUES IN CONSCIOUS AND ANESTHETIZED ALBINO-RAT [J].

SOKOLOFF, L ;

REIVICH, M ;

KENNEDY, C ;

DESROSIERS, MH ;

PATLAK, CS ;

PETTIGREW, KD ;

SAKURADA, O ;

SHINOHARA, M .

JOURNAL OF NEUROCHEMISTRY, 1977, 28 (05) :897-916

[59] THE PREPARATION OF C-11 LABELED FLUOROMETHANE FOR THE STUDY OF REGIONAL CEREBRAL BLOOD-FLOW USING POSITRON EMISSION TOMOGRAPHY [J].

STONEELANDER, S ;

ROLAND, P ;

ERIKSSON, L ;

LITTON, JE ;

JOHNSTROM, P ;

WIDEN, L .

EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1986, 12 (5-6) :236-239

[60]

WIDEN L, 1987, J CEREB BLOOD FLO S1, V7, pS485

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