Contiguous deletion syndromes

被引：67

作者：

Ballabio, Andrea ^{[1
]}

机构：

[1] Baylor Coll Med, Inst Mol Genet, One Baylor Plaza, Houston, TX 77030 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1991年 / 1卷 / 01期

关键词：

D O I：

10.1016/0959-437X(91)80036-L

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In the past few years, clinical, cytogenetic and molecular analysis of patients with complex phenotypes has led to the identification of syndromes caused by deletions of adjacent disease genes on a chromosome. These conditions, referred to as contiguous deletion syndromes, are an important component of the syndromes recognized in medical genetics, and the DNA from patients affected by these disorders is useful for the mapping and cloning of disease genes.

引用

页码：25 / 29

页数：5

共 32 条

[21] LEDBETTER DH, 1989, METABOLIC BASIS INHE, P343
[22] CLONING DEFINED REGIONS OF THE HUMAN GENOME BY MICRODISSECTION OF BANDED CHROMOSOMES AND ENZYMATIC AMPLIFICATION
LUDECKE, HJ
SENGER, G
CLAUSSEN, U
HORSTHEMKE, B
[J]. NATURE, 1989, 338 (6213) : 348 - 350
[23] MEMNGER T, 1990, AM J HUM GENET, V47, P664
[24] ISOLATION OF CANDIDATE CDNAS FOR PORTIONS OF THE DUCHENNE MUSCULAR-DYSTROPHY GENE
MONACO, AP
NEVE, RL
COLLETTIFEENER, C
BERTELSON, CJ
KURNIT, DM
KUNKEL, LM
[J]. NATURE, 1986, 323 (6089) : 646 - 650
[25] GENETIC IMPRINTING SUGGESTED BY MATERNAL HETERODISOMY IN NONDELETION PRADER-WILLI SYNDROME
NICHOLLS, RD
KNOLL, JHM
BUTLER, MG
KARAM, S
LALANDE, M
[J]. NATURE, 1989, 342 (6247) : 281 - 285
[26] PETIT C, 1990, HUM GENET, V85, P247
[27] Plants DAM, 1990, AM J HUM GENET, V47, P795
[28] COMPLETE PHYSICAL MAP OF THE WAGR REGION OF 11P13 LOCALIZES A CANDIDATE WILMS TUMOR GENE
ROSE, EA
GLASER, T
JONES, C
SMITH, CL
LEWIS, WH
CALL, KM
MINDEN, M
CHAMPAGNE, E
BONETTA, L
YEGER, H
HOUSMAN, DE
[J]. CELL, 1990, 60 (03) : 495 - 508
[29] RovER-PoKoRA B, 1986, NATURE, V322, P32
[30] CONTIGUOUS GENE SYNDROMES - A COMPONENT OF RECOGNIZABLE SYNDROMES
SCHMICKEL, RD
[J]. JOURNAL OF PEDIATRICS, 1986, 109 (02) : 231 - 241

← 1 2 3 4 →