SCHISTOSOMA-MANSONI - ACTIVITY RESPONSES INVITRO TO PRAZIQUANTEL

被引:24
作者
CHAVASSE, CJ [1 ]
BROWN, MC [1 ]
BELL, DR [1 ]
机构
[1] UNIV LIVERPOOL,BIOENGN & MED PHYS UNIT,LIVERPOOL L69 3BX,MERSEYSIDE,ENGLAND
来源
ZEITSCHRIFT FUR PARASITENKUNDE-PARASITOLOGY RESEARCH | 1979年 / 58卷 / 02期
关键词
D O I
10.1007/BF01951341
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The effects of praziquantel, a novel antischistosomal compound, on the activity of adult Schistosoma mansoni (Liverpool strain) in vitro were investigated. Worm activity was modified at all concentrations of praziquantel. High concentrations (above 0.5 μg/ml) produced rapid paralysis, whilst low concentrations of praziquantel stimulated worm activity. It is concluded that such activity modification could lead to worm displacement in vivo. © 1979 Springer-Verlag.
引用
收藏
页码:169 / 174
页数:6
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