SCHISTOSOMA-MANSONI - ACTIVITY RESPONSES INVITRO TO PRAZIQUANTEL

被引：24

作者：

CHAVASSE, CJ ^{[1
]}

BROWN, MC ^{[1
]}

BELL, DR ^{[1
]}

机构：

[1] UNIV LIVERPOOL,BIOENGN & MED PHYS UNIT,LIVERPOOL L69 3BX,MERSEYSIDE,ENGLAND

来源：

ZEITSCHRIFT FUR PARASITENKUNDE-PARASITOLOGY RESEARCH | 1979年 / 58卷 / 02期

关键词：

D O I：

10.1007/BF01951341

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The effects of praziquantel, a novel antischistosomal compound, on the activity of adult Schistosoma mansoni (Liverpool strain) in vitro were investigated. Worm activity was modified at all concentrations of praziquantel. High concentrations (above 0.5 μg/ml) produced rapid paralysis, whilst low concentrations of praziquantel stimulated worm activity. It is concluded that such activity modification could lead to worm displacement in vivo. © 1979 Springer-Verlag.

引用

页码：169 / 174

页数：6