PREPARATION OF DISUBSTITUTED EPICHLOROHYDRINS WITH TOTAL DIASTEREOSELECTIVITY - TRANSFORMATION OF ALPHA-BROMOCARBONYL COMPOUNDS INTO ALLYL ALCOHOLS

被引：17

作者：

BARLUENGA, J

LLAVONA, L

BERNAD, PL

CONCELLON, JM

机构：

[1] Departamento de Química Organometállica, Facultad de Química, Universidad de Oviedo

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 19期

关键词：

D O I：

10.1016/S0040-4039(00)93410-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Epichlorohydrins 3 have been obtained with total diastereoselectivity from alpha-bromocarbonyl compounds and chloromethyllithium generated in situ. The treatment of compounds 3 with lithium iodide or lithium powder affords allyl alcohols 4 in a regioselective manner.

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页码：3173 / 3176

页数：4

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