DISPOSITION OF MYCOPHENOLIC-ACID, BREVIANAMIDE-A, ASPERPHENAMATE, AND ERGOSTEROL IN SOLID CULTURES OF PENICILLIUM-BREVICOMPACTUM

被引：41

作者：

BIRD, BA ^{[1
]}

CAMPBELL, IM ^{[1
]}

机构：

[1] UNIV PITTSBURGH, DEPT BIOL SCI, PITTSBURGH, PA 15261 USA

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 1982年 / 43卷 / 02期

关键词：

D O I：

10.1128/AEM.43.2.345-348.1982

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

When P. brevicompactum was grown between layers of dialysis membrane on Czapek-Dox agar for 3 days, no synthesis of mycophenolic acid, brevianamide A, asperphenamate or ergosterol occurred. After removal of the uppermost membrane layer, aerial mycelium developed and all 4 metabolites were formed. The bulk of the mycophenolic acid that was formed was excreted into the medium, the bulk of the brevianamide A and asperphenamate occurred in the aerial hyphae, and ergosterol occurred in both vegetative and aerial mycelia.

引用

页码：345 / 348

页数：4

共 13 条

[11] Studies in the biochemistry of micro-organisms. XXX. The molecular constitution of the metabolic products of Penicillium brevi-compactum Dierckx and related species. I. The acids C-10,H10O5, C10H10O6 and C10H10O7.
Oxford, AE
Raistrick, H
[J]. BIOCHEMICAL JOURNAL, 1933, 27 : 634 - 653
[12] OXFORD AE, 1932, BIOCHEM J, V27, P1902
[13] 6-METHYLSALICYLIC ACID PRODUCTION IN SOLID CULTURES OF PENICILLIUM-PATULUM OCCURS ONLY WHEN AN AERIAL MYCELIUM IS PRESENT
PEACE, JN
BARTMAN, CD
DOERFLER, DL
CAMPBELL, IM
[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1981, 41 (06) : 1407 - 1412

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