ELECTROPHYSIOLOGIC INDICATION OF DEFECTIVE INFORMATION-STORAGE IN CHILDHOOD AUTISM

被引：54

作者：

NOVICK, B ^{[1
]}

KURTZBERG, D ^{[1
]}

VAUGHN, HG ^{[1
]}

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT NEUROSCI,BRONX,NY 10461

来源：

PSYCHIATRY RESEARCH | 1979年 / 1卷 / 01期

关键词：

Autism; cortical potentials; hippocampus; mesolimbic temporal cortex; posterior parietal cortex;

D O I：

10.1016/0165-1781(79)90034-9

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

We used a combined behavioral and electrophysiological technique to test the hypothesis that storage of information is impaired in childhood autism. Endogenous event-related potentials associated with the random deletion of stimuli within a regular train of auditory or visual stimuli were examined in three autistic and three normal children. We found that all subjects were able to detect the stimulus deletions, but cortical potentials associated with stimulus omissions were smaller or absent in the autistic subjects. These results are consistent with dysfunction within the system that includes posterior parietal cortex and its connections with the mesolimbic temporal cortex and hippocampus. © 1979.

引用

页码：101 / 108

页数：8

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