ELECTROPHYSIOLOGIC INDICATION OF DEFECTIVE INFORMATION-STORAGE IN CHILDHOOD AUTISM

被引：54

作者：

NOVICK, B ^{[1
]}

KURTZBERG, D ^{[1
]}

VAUGHN, HG ^{[1
]}

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT NEUROSCI,BRONX,NY 10461

来源：

PSYCHIATRY RESEARCH | 1979年 / 1卷 / 01期

关键词：

Autism; cortical potentials; hippocampus; mesolimbic temporal cortex; posterior parietal cortex;

D O I：

10.1016/0165-1781(79)90034-9

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

We used a combined behavioral and electrophysiological technique to test the hypothesis that storage of information is impaired in childhood autism. Endogenous event-related potentials associated with the random deletion of stimuli within a regular train of auditory or visual stimuli were examined in three autistic and three normal children. We found that all subjects were able to detect the stimulus deletions, but cortical potentials associated with stimulus omissions were smaller or absent in the autistic subjects. These results are consistent with dysfunction within the system that includes posterior parietal cortex and its connections with the mesolimbic temporal cortex and hippocampus. © 1979.

引用

页码：101 / 108

页数：8

共 15 条

[11]

Rutter, The development of autism, Psychological Medicine, 4, (1974)

[12]

Seltzer, Pandya, Some cortical projections to the perihippocampal area in the rhesus monkey, Experimental Neurology, 50, (1976)

[13]

Simson, Vaughan, Ritter, The scalp topography of potentials associated with missing visual or auditory stimuli, Electroencephalography and Clinical Neurophysiology, 40, (1976)

[14]

Van Hoesen, Pandya, Some connections of the entorhinal (area 28) and perirhinal (area 35) cortices of the rhesus monkey. I: Temporal lobe afferents, Brain Research, 95, (1975)

[15]

Vaughan, Toward a neuropsychology of schizophrenia, Journal of Psychiatric Research, 14, (1978)

← 1 2 →