RELEVANCE OF EARLY AGE-OF-ONSET IN GENETIC-STUDIES OF BIPOLAR AFFECTIVE-DISORDER

被引：83

作者：

STROBER, M ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES HOSP,LOS ANGELES,CA 90024

来源：

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY | 1992年 / 31卷 / 04期

关键词：

GENETICS; AGE-OF-ONSET; BIPOLAR ILLNESS;

D O I：

10.1097/00004583-199207000-00005

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Early age-of-onset appears to predict higher familial loading in bipolar affective disorder. This finding, coupled with ongoing attention to the importance of genomic heterogeneity for segregation and linkage analyses, underscores the value of research on juvenile samples. This research is reviewed, and implications for future research on genetic classification of bipolar illness are noted.

引用

页码：606 / 610

页数：5

共 59 条

[51]

Tsuang M, 1990, GENETICS MOOD DISORD

[52]

TSUANG MT, 1984, ARCH GEN PSYCHIAT, V41, P13

[53]

TSUANG MT, 1984, ARCH GEN PSYCHIAT, V41, P1136

[54] EARLY-ONSET MAJOR DEPRESSION IN PARENTS AND THEIR CHILDREN [J].