ZIRCONIUM CATALYZED C-C BOND FORMATION REACTION OF CONJUGATED DIYNES WITH ETMGBR

被引：34

作者：

TAKAHASHI, T ^{[1
]}

AOYAGI, K ^{[1
]}

DENISOV, V ^{[1
]}

SUZUKI, N ^{[1
]}

CHOUEIRY, D ^{[1
]}

NEGISHI, E ^{[1
]}

机构：

[1] PURDUE UNIV,DEPT CHEM,W LAFAYETTE,IN 47907

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(00)61416-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The carbon-carbon bond formation reactions of diynes with EtMgBr can be catalyzed by Cp(2)ZrCl(2). The final products, magnesiated enynes, readily undergo stereoisomerization to give a mixture of (E) and (Z) isomers. The stoichiometric reaction of diynes with ethylene zirconocene gives zirconacyclopentenes with alkynyl substituents in the alpha position with high regioselectivities.

引用

页码：8301 / 8304

页数：4

共 38 条

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