SYNTHESIS OF GAMMA-HALOESTERS AND GAMMA-KETOESTERS BY HOMOLYTIC ADDITION OF CARBON RADICALS GENERATED BY ALPHA-HALOESTERS AND TRIETHYLBORANE TO ALKENES AND SILYL ENOL ETHERS

被引：28

作者：

BACIOCCHI, E ^{[1
]}

MURAGLIA, E ^{[1
]}

机构：

[1] CNR,CTR STUDIO MECCANISMI REAZ,I-00185 ROME,ITALY

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 17期

关键词：

D O I：

10.1016/S0040-4039(00)77027-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of gamma-haloesters has been achieved, under very mild conditions, by addition of electrophilic carbon radicals .CH(R)CO(2)Et (R=H, Me, CO(2)Et) generated by XCH(R)CO(2)Et (X=Br, I) / BEt(3) / air in DMSO to alkenes and cycloalkenes. The synthesis of gamma-ketoesters is also possible when silyl enol ethers are used as the substrates.

引用

页码：2763 / 2766

页数：4

共 9 条

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