ENANTIOSELECTIVE ADDITION-REACTION OF TRIMETHYLSILYL CYANIDE WITH ALDEHYDES USING A CHIRAL TIN(II) LEWIS ACID

被引：95

作者：

KOBAYASHI, S

TSUCHIYA, Y

MUKAIYAMA, T

机构：

来源：

CHEMISTRY LETTERS | 1991年 / 04期

关键词：

D O I：

10.1246/cl.1991.541

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Trimethylsilyl cyanide (TMS-CN) enantioselectively reacts with aldehydes to afford the corresponding cyanohydrin trimethylsilyl ethers in good yields in the presence of a chiral tin(II) Lewis acid prepared from 1,1'-dimethylstannocene, triflic acid and (+)-cinchonine.

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页码：541 / 544

页数：4

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