DAPHNIPHYLLUM ALKALOIDS .8. ASYMMETRIC TOTAL SYNTHESIS OF (-)-SECODAPHNIPHYLLINE

被引：73

作者：

STAFFORD, JA ^{[1
]}

HEATHCOCK, CH ^{[1
]}

机构：

[1] UNIV CALIF BERKELEY,DEPT CHEM,BERKELEY,CA 94720

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 20期

关键词：

D O I：

10.1021/jo00307a006

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An asymmetric total synthesis of (-)-seco-daphniphylline (5) is described. The desired absolute stereochemistry is established in two stereoselective transformations—an asymmetric Michael reaction of amide 8 and an asymmetric reduction of ketone 14. © 1990, American Chemical Society. All rights reserved.

引用

页码：5433 / 5434

页数：2

共 25 条

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[22] NEW DAPHNIPHYLLUM ALKALOIDS, DEOXYYUZURIMINE AND ISODAPHNILACTONE-B
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