TOTAL SYNTHESIS OF (-)-CARBOVIR

被引：45

作者：

JONES, MF

MYERS, PL

ROBERTSON, CA

STORER, R

WILLIAMSON, C

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 10期

关键词：

D O I：

10.1039/p19910002479

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically pure (-)-carbovir has been prepared by two different routes involving stereospecific opening of chiral cyclopentene epoxides by substituted purines. Introduction of the 2',3' unsaturation was accomplished by mesylate elimination, either after introduction of the purine (Route 1), or earlier in the sequence, producing a novel vinyl epoxide (Route 2).

引用

页码：2479 / 2484

页数：6

共 15 条

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