SYNTHESIS AND ANTI-HIV ACTIVITY OF DIFFERENT SUGAR-MODIFIED PYRIMIDINE AND PURINE NUCLEOSIDES

被引：137

作者：

HERDEWIJN, P ^{[1
]}

BALZARINI, J ^{[1
]}

BABA, M ^{[1
]}

PAUWELS, R ^{[1
]}

VANAERSCHOT, A ^{[1
]}

JANSSEN, G ^{[1
]}

DECLERCQ, E ^{[1
]}

机构：

[1] CATHOLIC UNIV LEUVEN,REGA INST MED RES,MINDERBROEDERSSTR 10,B-3000 LOUVAIN,BELGIUM

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 10期

关键词：

D O I：

10.1021/jm00118a033

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：2040 / 2048

页数：9

共 61 条

[1] THE SYNTHESIS OF SOME BRANCHED-CHAIN-SUGAR NUCLEOSIDE ANALOGS
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[2] BOTH 2',3'-DIDEOXYTHYMIDINE AND ITS 2',3'-UNSATURATED DERIVATIVE (2',3'-DI-DEOXYTHYMIDINENE) ARE POTENT AND SELECTIVE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS-REPLICATION INVITRO
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[3] SELECTIVE-INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) BY 3'-AZIDO-2',3'-DIDEOXYGUANOSINE INVITRO
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[4] THE 2',3'-DIDEOXYRIBOSIDE OF 2,6-DIAMINOPURINE SELECTIVELY INHIBITS HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) REPLICATION INVITRO
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[5] BALZARINI J, 1987, MOL PHARMACOL, V32, P798
[6] POTENT AND SELECTIVE ANTI-HTLV-III/LAV ACTIVITY OF 2',3'-DIDEOXYCYTIDINENE, THE 2',3'-UNSATURATED DERIVATIVE OF 2',3'-DIDEOXYCYTIDINE
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[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 140 (02) : 735 - 742
[7] BALZARINI J, 1988, MOL PHARMACOL, V33, P243
[8] ANTI-RETROVIRUS ACTIVITY OF 3'-FLUORO-SUBSTITUTED AND 3'-AZIDO-SUBSTITUTED PYRIMIDINE 2',3'-DIDEOXYNUCLEOSIDE ANALOGS
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[J]. BIOCHEMICAL PHARMACOLOGY, 1988, 37 (14) : 2847 - 2856
[9] BALZARINI J, 1987, MOL PHARMACOL, V32, P162
[10] BALZARINI J, IN PRESS DEV MED VIR

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