C-BIFUNCTIONAL SILACYCLOPENTANES AND GERMACYCLOPENTANES .1. 1-SILACYCLOPENTAN-2,3-DIOLS AND 1-GERMACYCLOPENTAN-2,3-DIOLS AND 1-GERMACYCLOPENTAN-3,4-DIOLS

被引：14

作者：

MANUEL, G

BOUKHERROUB, R

机构：

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 1993年 / 447卷 / 02期

关键词：

D O I：

10.1016/0022-328X(93)80235-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

C-bifunctional sila- and germacyclopentanes have some potential as biologically active drugs. Ten representative 1-sila (and 1-germa) cyclopentane-2,3 and 3,4-diols, cis or trans, were synthesized from the corresponding 1-metallacyclopen-3-enes. The influence of the metal, silicon or germanium, on each step leading to 3 sets of alpha-diols is underlined. The stereochemistry of the alpha-diols and their precursors was established by H-1 and C-13 NMR spectroscopy.

引用

页码：167 / 175

页数：9

共 32 条

[11] ASPECTS OF STEREOCHEMISTRY .1. STEREOSPECIFICITY IN FORMATION OF EPOXIDES FROM CYCLIC ALLYLIC ALCOHOLS
HENBEST, HB
WILSON, RAL
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1957, (MAY): : 1958 - 1965
[12] FLASH VACUUM PYROLYSIS (FVP) OF 2,7-DIMETHYL-2,3-7,8-DIEPOXY-5-SILASPIRO[4.4]NONANE(I) WITH CYCLOTRISILOXANES - SYNTHESIS OF SPIROCYCLOSILOXANES - CHARACTERIZATION OF SILICA FORMED BY FVP OF I
HENRY, GK
DOWD, DR
BAU, R
MANUEL, G
WEBER, WP
[J]. ORGANOMETALLICS, 1986, 5 (09) : 1818 - 1823
[13] SYNTHESIS OF SPIROCYCLOSILOXANES BY FLASH VACUUM PYROLYSIS OF 2,7-DIMETHYL-2,3-7,8-DIEPOXY-5-SILASPIRO[4.4]NONANE AND CYCLOSILOXANES
JUENGST, CD
WEBER, WP
MANUEL, G
[J]. JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1986, 308 (02) : 187 - 194
[14] INSERTION REACTIONS OF DIMETHYLGERMANONE [(CH3)2GE=0] INTO SI-O AND SI-CL BONDS
KANG, KT
MANUEL, G
WEBER, WP
[J]. CHEMISTRY LETTERS, 1986, (10) : 1685 - 1686
[15] STERIC CONTROL OF EPOXIDATION BY ALLYLIC AND HOMOALLYLIC CARBAMATE GROUPS
KOCOVSKY, P
[J]. TETRAHEDRON LETTERS, 1988, 29 (20) : 2475 - 2478
[16] 6-THIA-3,3-DIPHENYL-3-SILA-(AND 3-GERMA-)BICYCLO[3.1.0]HEXANES
MANUEL, G
FAUCHER, A
MAZEROLLES, P
[J]. JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1987, 327 (02) : C25 - C28
[17] SYNTHESIS AND REACTIVITY OF 1-SILACYCLOPENTAN-2-OLS - FORMATION OF 1-OXA-2-SILACYCLOHEXANES BY RING EXPANSION REACTION
MANUEL, G
MAZEROLLES, P
GRIL, J
[J]. JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1976, 122 (03) : 335 - 343
[18] TRANSITION FROM BETA TO ALPHA SILACYCLOPENTENES
MANUEL, G
MAZEROLL.P
DARBON, JM
[J]. JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1973, 59 (OCT1) : C7 - C10
[19] AN IMPROVED SYNTHESIS OF KEY INTERMEDIATES IN METALLOLE 4B CHEMISTRY
MANUEL, G
BERTRAND, G
ELANBA, F
[J]. ORGANOMETALLICS, 1983, 2 (03) : 391 - 394
[20] THERMOLYSIS OF 6-OXA-3-SILABICYCLO[3.1.0]HEXANES - A NEW CONVENIENT ROUTE TO SILICON OXYGEN PI-BONDED SPECIES
MANUEL, G
BERTRAND, G
WEBER, WP
KAZOURA, SA
[J]. ORGANOMETALLICS, 1984, 3 (09) : 1340 - 1343

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