STRUCTURE AND METABOLISM OF LIPOPROTEIN (A)

被引：50

作者：

MARCOVINA, SM

MORRISETT, JD

机构：

[1] UNIV WASHINGTON,DEPT MED,NW LIPID RES LABS,SEATTLE,WA 98103

[2] BAYLOR COLL MED,DEPT MED,DIV ATHEROSCLEROSIS & LIPOPROT RES,HOUSTON,TX

来源：

CURRENT OPINION IN LIPIDOLOGY | 1995年 / 6卷 / 03期

关键词：

D O I：

10.1097/00041433-199506000-00005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An understanding of the complex structural and metabolic features of lipoprotein (a) is essential because this lipoprotein particle, with poorly recognized physiological functions, has been implicated in both thrombogenesis and atherogenesis. Studies aimed at investigating the structure-function relationship of apolipoprotein (a) have generated new useful information. In-vivo and in-vitro studies have provided insights into the synthesis, secretion, and association of apolipoprotein (a) with apolipoprotein B-100 and the mechanisms regulating the lipoprotein (a) concentration in the bloodstream.

引用

页码：136 / 145

页数：10

共 56 条

[31] IN-VIVO KINETICS OF LIPOPROTEIN(A) IN HOMOZYGOUS WATANABE HERITABLE HYPERLIPEMIC RABBITS [J].