LABELING OF 4-ALKYLAMINO-IODOQUINOLINES WITH RADIOACTIVE IODINE BY ISOTOPIC EXCHANGE

被引：6

作者：

BAKKER, CNM ^{[1
]}

KASPERSEN, FM ^{[1
]}

机构：

[1] IOI,NETHERLANDS OPHTHALM RES INST,NL-1009 AJ AMSTERDAM,NETHERLANDS

来源：

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 1979年 / 16卷 / 06期

关键词：

isotopic exchange; melanoma; radioactive chloroquine‐analogs; radioactive iodine‐compounds; Radiopharmaceuticals;

D O I：

10.1002/jlcr.2580160614

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

4‐alkylamino‐iodoquinolines can be labeled as their phosphate salts in high yields and in a short period of time by nucleophilic exchange in a melt with radioactive iodide. The iodide must be free of NaCl and reducing agents. Copyright © 1979 John Wiley & Sons, Ltd.

引用

页码：917 / 928

页数：12

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