DERACEMIZATION OF A PHOSPHINE OXIDE VIA ENANTIOSELECTIVE PROTONATION

被引：26

作者：

VEDEJS, E

GARCIARIVAS, JA

机构：

[1] Chemistry Department, University of Wisconsin, Madison

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 22期

关键词：

D O I：

10.1021/jo00101a008

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of the phosphine oxide anion 2 with the keto aniline 3c affords (S)-1 with 81-83% ee, and one crystallization upgrades the material to (S)-1 with > 99% ee (78% overall yield).

引用

页码：6517 / 6518

页数：2

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